Splitting tablets into two or more parts is potentially dangerous and could lead to people taking the wrong dose, warns researchers.
There could be serious consequences, especially with pills that have a narrow margin between a therapeutic and a toxic dose, Splitting means tablet parts are often unequal in size. Researchers found that 31 percent of split tablets deviated from the recommended dose by at least 15 percent and sometimes by more than 25 percent. The study involved drugs prescribed for Parkinson`s disease, congestive heart failure, thrombosis and arthritis, among others.